Sweet research morsels to chew on

W.What is the relationship between suicidal behavior and the immune system? Is there a way to distinguish between a high risk of mania and depression? What about that brain map developed by Google and Harvard?

In that single cubic millimeter, which is one millionth the size of the brain, there are approximately 57,000 cells (neurons), about 230 millimeters of blood vessels and almost 150 million neuronal synapses.

We return to a feature that was once common here.

There is a lot of research being done in the world of emotional and mental health illnesses. And we needed to find a way to inform readers from time to time.

“Chips from the old block” worked well. And it seemed right to bring him back.

Let’s go have a few bites…

A study reveals new details about the relationship between suicidal ideation/attempt and alterations in the immune system

from the Brain and Behavior Research Foundation

A study of immune activation and function in patients with major depressive disorder (MDD) and bipolar disorder (BD) revealed that innate and acquired (adaptive) mechanisms immune system They are altered in patients who have had at least one episode of suicidal ideation or attempt.

Inflammation is one of the byproducts of immune system activation. Inflammation that causes physical pain is well known and understood. However, that is not the case with psychiatric illnesses.

With support from the Brain & Behavior Research Foundation (BBRF), Dr. Federico Manuel Daray, Ph.D., of the University of Buenos Aires, embarked on research dedicated to better understanding the possible functions of the immune system in the development and maintenance of depression.

The work of Dr. Daray and his colleagues has yielded many potentially important insights, broadly showing that both the innate and acquired immune systems are altered in patients with suicidal ideation or attempts across the lifespan.

How about this from Dr. Daray: “We wondered whether what we were seeing in suicidal people was due to depression or not,” he continued, “These findings have potential therapeutic implications, suggesting that for patients with suicidal thoughts or attempts Inflammation may be necessary in addition to treating previously identified depressive symptoms.”

Give it a read.

Neural activation patterns that may help distinguish elevated risk of mania/hypomania from risk of depression in youth

risk of depression in young people

from the Brain and Behavior Research Foundation

Researchers have identified several patterns of brain activity in young adults that appear to distinguish elevated risk of mania/hypomania from elevated risk of depression.

This is huge because, if validated, the patterns could serve as biomarkers, facilitating earlier diagnosis of bipolar disease.

Keep in mind that the first symptoms a patient experiences may be those of depression. But is depression unipolar or bipolar? The only distinguishing factor is having at least one episode of mania or hypomania. But how long will it be until that happens?

BBRF Scientific Council member Mary L. Phillips, MD, and colleagues at the University of Pittsburgh recently published a paper reporting several distinctive patterns of brain activity in young adults.

In their analysis, the team was able to determine that certain patterns of brain activation and neural network connectivity were specific to an elevated risk of mania/hypomania, as well as depression.

The “robust associations” the team found may not only help distinguish the two conditions, but also provide neural targets to guide and monitor interventions in those at risk for BD and other affective disorders.

Give it a read.

Google helped create an exquisitely detailed map of a small part of the human brain

Exquisitely detailed Google map

Google research

A team led by scientists from Harvard and Google has created a 3D map with nanoscale resolution of a single cubic millimeter of the human brain. To get an idea of ​​the size in volume: one cubic millimeter = 0.001 milliliters, one milliliter = one thousandth of a liter.

In that single cubic millimeter, which is one millionth the size of the brain, there are approximately 57,000 cells (neurons), about 230 millimeters of blood vessels and almost 150 million neuronal synapses.

Interesting: finding a piece of brain tissue was a challenge. Since it deteriorates quickly after death, cadaveric tissue would not function. Well, they took a piece of the brain from a woman who was undergoing surgery to help control her seizures.

Of the project, Michael Hawrylycz, a computational neuroscientist at the Allen Institute, said: “It’s probably the most computationally intensive work in all of neuroscience.” According to Seth Ament, a neuroscientist at the University of Maryland, “the ability to obtain such a deep reconstruction of any human brain sample is an important advance.”

The map, which is freely available on a web platform called neuroviewer, is intended to be a resource that other researchers can use to make and publish their own discoveries. How important is that?

By the way, those are excitatory neurons in the image. They are colored based on depth from the surface of the brain, with blue being the closest.

Give it a read.

Bringing great hope

We are pleased that “Chips off the old block” is back up and running.

There is a lot of active research in the world of emotional and mental health illnesses. And it’s important to share some of what’s going on.

It brings great hope.


All kinds of information about Chipur and inspirational articles are waiting for you. Examine the titles.

We will be happy to hear your thoughts

Leave a reply

Probuyers-shop
Logo
Register New Account
Compare items
  • Total (0)
Compare
0
Shopping cart